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IFRA Annual Report
  • Home
  • IFRA Regions
    • Asia Pacific (APAC)
    • Europe
    • India
    • Latin America (LATAM)
  • Science & Regulation
    • CITES Convention
    • Furocoumarins policy
    • IDEA project
    • IFRA Standards
    • New Approach Methods
    • Regulatory affairs
  • Communications
  • Sustainability
  • About
    • IFRA Board
    • IFRA team
    • Committees & task forces
Supporting the shift away from animal testing

New Approach Methodologies (NAMs)

 A global paradigm shift in chemical testing guidelines has been observed, recognizing the limitations of animal testing and the growing preference for New Approach methodologies (NAMs). In 2024, there was a milestone Achieved in the use of NAMs.

New Approach Methodologies - 2024 milestone

Acetylated Vetiver Oil (AVO): First for use of NAMs

In 2024, IFRA’s consortium addressed inhalation safety concerns for Acetylated Vetiver Oil (AVO), a key fine fragrance ingredient. Using a New Approach Methodology (NAM), they presented experimental data to the SCCS, which issued a positive opinion supporting AVO’s safety in sprayable applications. 


This marked a milestone as it was the first use of a NAM in vitro method for this endpoint on a complex fragrance ingredient. In 2025, the consortium will publish findings to guide future safety assessments. 


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