Perfume bottles, a reed diffuser and handwritten notes on swirls of teal

Chapter 03 · Science and regulation

Labelling Manual and CLH proposals

Two interviews1 min read

Watch the interviewWatched Cristina ArreguiYouTube

Cristina ArreguiGlobal Regulatory Affairs Director

Interview 1 of 2

2025 update to the IFRA–IOFI Labelling Manual

Ensuring consistent and credible hazard communication

Cristina Arregui, Global Regulatory Affairs Director at IFRA, explains the importance of the 2025 update to the IFRA–IOFI Labelling Manual. The Manual gives essential guidance on applying the rules of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) to fragrance and flavor ingredients, ensuring clarity and consistency across the industry.

A harmonized interpretation of hazard data is critical to avoid conflicting classifications for the same substance and to maintain trust throughout the supply chain. The approach aligns with EU principles under REACH and CLP, encouraging data sharing and consensus-building. By speaking with one voice, the industry is better placed to support robust scientific positions and engage effectively with regulators.

Watch the interviewWatched Cristina ArreguiYouTube

Cristina ArreguiGlobal Regulatory Affairs Director

Interview 2 of 2

CLH proposals and the regulatory context

Advocating for proportionate, science-based classification

Cristina Arregui explains how work on the IFRA–IOFI Labelling Manual supports IFRA’s engagement on EU proposals for harmonized classification and labeling (CLH). By aligning on a robust, coherent interpretation of hazard data, the industry is better placed to advocate for a pragmatic application of the CLP rules.

IFRA promotes classifications that reflect human relevance, informed by mechanistic evidence and realistic exposure, rather than effects seen only at extreme test doses. This matters particularly for fragrance ingredients, which are used at very low levels but can face significant regulatory consequences. IFRA’s message remains clear: consumer protection must be evidence-based, proportionate and compatible with innovation.

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Communications

How IFRA told its story in 2025, and how it served Members and stakeholders.

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