IFRA's regulatory affairs department worked on the IFRA-IOFI GHS Labelling Manual and CLH proposals
Cristina Arregui, Global Regulatory Affairs Director at IFRA, highlights the importance of the 2025 update to the IFRA–IOFI Labelling Manual.
The Manual provides essential guidance on the application of GHS classification and labelling rules to fragrance and flavour ingredients, ensuring clarity and consistency across the industry. Harmonised interpretation of hazard data is critical to avoid conflicting classifications for the same substance and to maintain trust throughout the supply chain.
The approach aligns with EU principles under REACH and CLP, encouraging data sharing and consensus-building. By speaking with one voice, the industry is better positioned to support robust scientific positions and engage effectively with regulators.
Cristina Arregui, Global Regulatory Affairs Director at IFRA, explains how work on the IFRA–IOFI Labelling Manual supports engagement on EU harmonised classification and labelling (CLH) proposals.
By aligning on robust, coherent interpretation of hazard data, the industry is better placed to advocate for pragmatic application of CLP rules. IFRA promotes classifications that reflect human relevance, informed by mechanistic evidence and realistic exposure, rather than effects seen only at extreme test doses.
This is particularly important for fragrance ingredients, which are used at very low levels but can face significant regulatory consequences. IFRA’s message remains clear: consumer protection must be evidence-based, proportionate and compatible with innovation.